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Glycoprotein fraction isolated from wheat bran and method for producing the same

机译:从麦麸分离的糖蛋白级分及其生产方法

摘要

The present invention relates to a glycoprotein derived bran fraction and methods for their preparation, are in more detail (a ) steps to skim bran; (B) the pH of the buffer solution of 7.0 to 8.0 mixture of bran; (C) obtaining a supernatant by centrifuging the mixture; (D) the dialysis step of the supernatant by dialysis, the semipermeable membrane (MWCO 6000-8000); Step (e) precipitating the protein by the addition of salt to precipitate per protein in the supernatant dialyzed; (F) step of dialysis with a semipermeable membrane dialysis (MWCO 6000-8000) was dissolved in a buffer solution the pH of the precipitate in 7.0 to 8.0; And (g) promote been manufactured by a method comprising the step of obtaining a glycoprotein fraction from the dialyzed lysate precipitated, the immune function of the molecular weight, and it contains a bran fraction-derived glycoproteins, characterized in that the active ingredient of 16 to 70kDa for the pharmaceutical, the present invention relates to a food composition. Glycoprotein fraction of the present invention for enhancing drugs which activate the immune activity of macrophages Crescent Steen (PSK) very good in efficacy to stimulate cytotoxic than not at all, and is effective for new functional food and pharmaceutical manufacturing for enhancing immune function. ;
机译:本发明涉及糖蛋白衍生的麸级分及其制备方法,更详细地是:(a)脱脂麸的步骤; (b)缓冲溶液的pH为7.0至8.0的麸皮混合物; (C)通过离心混合物获得上清液; (D)透析步骤是通过透析上清液,半透膜(MWCO 6000-8000);步骤(e)通过加入盐使蛋白质沉淀以使每个蛋白质在透析的上清液中沉淀; (F)用半透膜透析步骤(MWCO 6000-8000)进行透析,将沉淀的pH值溶解在7.0至8.0的缓冲溶液中;并且(g)促进剂的制造方法包括以下步骤:从沉淀的透析的裂解物中获得糖蛋白级分,分子量的免疫功能,并且其包含麸皮级分的糖蛋白,其特征在于活性成分为16用于药物的至70kDa,本发明涉及食品组合物。本发明的用于增强激活巨噬细胞新月体(PSK)的免疫活性的药物的糖蛋白级分在根本上根本没有刺激细胞毒性的功效非常好,并且对于增强免疫功能的新型功能性食品和药物生产是有效的。 ;

著录项

  • 公开/公告号KR101467350B1

    专利类型

  • 公开/公告日2014-12-03

    原文格式PDF

  • 申请/专利权人

    申请/专利号KR20120132909

  • 申请日2012-11-22

  • 分类号C07K1/34;C07K1/36;C07K14/415;A23L1/29;

  • 国家 KR

  • 入库时间 2022-08-21 15:01:08

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