FUSION PROTEIN COMPRISING ANNEXIN A2 BINDING PROTEIN, P53 AND P18, AND COMPOSITION COMPRISING THE FUSION PROTEIN FOR PREVENTING OR TREATING CANCER

摘要

The present invention relates to a fusion protein having an annexin A2 binding protein, a p53 protein, and a p18 protein bound, and to a pharmaceutical composition including the fusion protein for preventing or treating a cancer. Provided in an embodiment of the present invention is a fusion protein including an annexin A2 binding protein, a p53 protein or a fragment of the same, and a p18 protein. The fusion protein can additionally include one or more selected from the group consisting of an in vitro stabilization protein, a membrane transfer sequence (MTS) domain, a nucleus-cytoplasm signal domain, ATT, and STOPx2.