AUTOLOGOUS AND ALLOGENIC ADIPOSE TISSUE-DERIVED MESENCHYMAL STEM CELLS COMPOSITION FOR TREATMENT OF DIABETIC WOUND

摘要

The present invention relates to a pharmaceutical composition for treating diabetic wound which is prepared by suspending stromal stem cells originated from human adipose tissues into a stem cell medium comprising highly concentrated cell growth factors, and to a technique which transplants the composition and biodegradable scaffold into a human body. The stem cell composition comprising the stem cell medium obtained by the method of the present invention: has more cell growth factors, especially vascular regeneration related VEGF, than using the stem cells only, thereby being appropriate for clinical use; and inhibits immune responses in transplanted area by the adipose tissue-derived mesenchymal stem cells if the implantable stem cell composition for treating wound is used with the scaffold for autologous and allogenic transplantation, thereby being clinically useful for enhancing wound treatment, especially for diabetic wound treatment.