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COMPOSITIONS FOR PREVENTING OR IMPROVING OF ALCOHOLIC LIVER DISEASE, OR REDUCING ALCOHOLIC HANGUP COMPRISING ROSA RUGOSA EXTRACTS
COMPOSITIONS FOR PREVENTING OR IMPROVING OF ALCOHOLIC LIVER DISEASE, OR REDUCING ALCOHOLIC HANGUP COMPRISING ROSA RUGOSA EXTRACTS
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机译:用于预防或改善酒精性肝病或减少含ROSA RUGOSA提取物的酒精残留的组合物
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摘要
The present invention relates to a composition comprising a Rosa rugosa extract as an active ingredient for preventing or alleviating an alcoholic liver disease. The composition of the present invention has relatively high scavenging activity in scavenging a DPPH radical and an ABTS radical, has an aspartic acid, asparagine, serin, glycine, arginine or allicin which promotes the generation of alcoholysis enzymes and inhibits the activity of a CYP2E1 enzyme which causes an alcoholic liver damage to obstruct a reduction in the viability of HepG2 cells caused by an alcohol. In addition, the composition has no cytotoxicity in liver cells causing a alcoholic liver damage, thereby being safely used in a pharmaceutical and a food composition.
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