METHODS OF PREVENTING TUMOR METASTASIS, TREATING AND PROGNOSING CANCER AND IDENTIFYING AGENTS WHICH ARE PUTATIVE METASTASIS INHIBITORS

摘要

The present invention provides a method for preventing metastasis of a tumor, provided that the tumor is not a glioblastoma. The method comprises administering to a subject in need thereof a therapeutically effective amount of an inhibitor of synaptotoxin 2 (SYNJ2) and thereby preventing metastasis of the tumor. The present invention also provides a method of treating cancer. The method comprises administering to a subject in need thereof a therapeutically effective amount of an inhibitor of synaptotoxin 2 (SYNJ2) and an inhibitor of a cell surface receptor associated with the onset or progression of cancer, and thereby treating the cancer .