首页> 外国专利> ISCHEMIC DISEASE TREATING COMPOSITION CONTAINING AMNIOTIC MESENCHYMAL STEM CELLS

ISCHEMIC DISEASE TREATING COMPOSITION CONTAINING AMNIOTIC MESENCHYMAL STEM CELLS

机译:包含羊膜间充质干细胞的缺血性疾病治疗组合物

摘要

The present invention relates to a pharmaceutical composition containing a pharmaceutically effective amount of amniotic mesenchymal stem cells (AMMs) and a pharmaceutically acceptable support for treating ischemic diseases. The amniotic mesenchymal stem cells according to the present invention express and secrete genes and proteins associated with chemotactic properties, cell migration, and angiogenic properties at a high level as compared with an adipose-derived mesenchymal stem cell. Moreover, the AMMs reduce myocardial infarction; significantly increases the vascular density; promote secretion of multiple paracrine factors; significantly increase left ventricular ejection fraction (LVEF); and thus can be advantageously used for treating ischemic diseases.;COPYRIGHT KIPO 2015
机译:本发明涉及一种药物组合物,其包含药学上有效量的羊膜间充质干细胞(AMM)和药学上可接受的用于治疗缺血性疾病的载体。与脂肪来源的间充质干细胞相比,本发明的羊膜间充质干细胞以高水平表达和分泌与趋化特性,细胞迁移和血管生成特性相关的基因和蛋白质。此外,AMM可以减少心肌梗塞。显着增加血管密度;促进多种旁分泌因子的分泌;显着增加左心室射血分数(LVEF);因此可以有利地用于治疗缺血性疾病。; COPYRIGHT KIPO 2015

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