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AZAINDOLE DERIVATIVES, C-KIT INHIBITORING COMPOSITION AND PHARMACEUTICAL COMPOSITIONS FOR TREATMENT OF DISEASES LINKED TO C-KIT COMPRISING THE SAME
AZAINDOLE DERIVATIVES, C-KIT INHIBITORING COMPOSITION AND PHARMACEUTICAL COMPOSITIONS FOR TREATMENT OF DISEASES LINKED TO C-KIT COMPRISING THE SAME
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机译:氮杂吲哚衍生物,C-KIT抑制组合物和药物组合物,用于治疗与C-KIT相关的疾病
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摘要
The present invention relates to an azaindole derivative compound represented by chemical formula 1, a c-kit D816V mutant comprising the same as an active ingredient and c-kit wild type (WT) inhibitor composition. A composition according to the present invention can efficiently inhibit expression of a c-kit D816V mutant as well as a c-kit WT and thus can be used for treating a c-kit D816V mutant and a c-kit WT-related diseases, especially, cancer.
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