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c-KIT c-KIT Azaindole derivatives c-KIT inhibitoring composition and pharmaceutical compositions for treatment of diseases linked to c-KIT comprising the same
c-KIT c-KIT Azaindole derivatives c-KIT inhibitoring composition and pharmaceutical compositions for treatment of diseases linked to c-KIT comprising the same
The present invention relates to an azaindole derivative represented by the following formula (1), a c-KIT D816V mutant and a c-KIT wild type (WT) inhibitory composition comprising the same as an active ingredient. WT as well as the expression of the c-KIT D816V mutant and thus can be used for the treatment of diseases associated with the c-KIT D816V mutation and the c-KIT wild type (WT), particularly cancer. [Chemical Formula 1]
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