首页> 外国专利> MICROFLUIDIC CHIP WITH MICROCHANNELS FILLED WITH NANOFIBERS AND ITS FABRICATION METHOD

MICROFLUIDIC CHIP WITH MICROCHANNELS FILLED WITH NANOFIBERS AND ITS FABRICATION METHOD

机译:纳米纤维填充微通道的微流控芯片及其制备方法

摘要

The present invention relates to a microchannel biochip equipped with a microchannel unit filled with nanofibers and a method for producing the same. More specifically, the microchannel biochip includes a bottom plate and a top plate produced by being laminated on the top surface of the bottom plate. The top plate comprises: a microchannel unit formed in a tapered shape, in which the cross sectional shape thereof in a thickness direction is gradually widened, and consisting of a microchannel and a side end part of the end of the microchannel; and a chamber unit connected with the side end part and formed in a hole shape through which the top surface and bottom surface of the top plate pass. The side end part is formed in a shape which has a gradually increasing width from the microchannel to the chamber unit in order to be connected with the chamber unit. Also, polymer nanofibers are filled in all or a part of the microchannel unit. Nanofibers are filled in a microchannel which has not been indicated in existing biochips, and cells can be included in an environment similar to the inside of a human body, so that the movement of the cells can be three-dimensionally expanded.
机译:本发明涉及一种配备有填充有纳米纤维的微通道单元的微通道生物芯片及其生产方法。更具体地,微通道生物芯片包括底板和通过层压在底板的顶表面上而产生的顶板。顶板包括:形成为锥形的微通道单元,其中其在厚度方向上的横截面形状逐渐变宽,并且由微通道和微通道的端部的侧端部组成。腔室单元,其与侧端部连接并且形成为孔形状,顶板的顶表面和底表面穿过该孔单元。侧端部形成为从微通道到腔室单元的宽度逐渐增大的形状,以便与腔室单元连接。而且,聚合物纳米纤维填充在全部或部分微通道单元中。纳米纤维被填充在现有生物芯片中未曾指出的微通道中,并且细胞可以被包含在类似于人体内部的环境中,从而可以在三维方向上扩展细胞的运动。

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