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DNA Aptamer Specifically Binding to Alpha-fetoprotein and Its Use

机译:DNA适体特异性结合甲胎蛋白及其应用

摘要

The present invention is capable of specifically binding to the AFP (Alpha-fetoprotein) relates to a DNA aptamer and its purpose . Liver or has a DNA aepta dimmer marker proteins AFP and specifically to binding characteristics of germ cell tumors of the present invention . Thus , as well as the use of DNA detection aepta dimmer AFP of the present invention , by measuring the level of AFP, liver and reproductive cells can be used as diagnostic or prognostic use of the tumor is determined . Can replace the AFP binding antibody that is utilized in the DNA of liver cancer diagnosis aepta dimmer of the present invention, the more quickly the germ cell tumors and liver cancer and is expected to be diagnosed economically . ;
机译:本发明能够特异性结合涉及DNA适体的AFP(甲胎蛋白)及其目的。肝或具有DNA aepta二聚体标记蛋白的AFP,并特异性地结合本发明生殖细胞肿瘤的特征。因此,以及使用本发明的DNA检测七肽二聚体AFP,通过测量AFP的水平,可以将肝脏和生殖细胞用作诊断或预后判断肿瘤的用途。可以替代用于本发明的肝癌诊断Aepta二聚体的DNA中的AFP结合抗体,生殖细胞肿瘤和肝癌越快并且有望被经济地诊断。 ;

著录项

  • 公开/公告号KR1015137660000B1

    专利类型

  • 公开/公告日2015-04-20

    原文格式PDF

  • 申请/专利权人

    申请/专利号KR1020110012878

  • 发明设计人 김양훈;엄현주;연승용;

    申请日2011-02-14

  • 分类号C12N15/115;C12Q1/68;

  • 国家 KR

  • 入库时间 2022-08-21 14:58:19

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