REDOX REBALANCING METHOD IN E. COLI STRAIN FOR MAXIMIZING FERMENTATION PRODUCT PRODUCTION AND RECOMBINANT E. COLI STRAIN FOR PRODUCING N-BUTANOL PRODUCT WITH HIGH PRODUCTIVITY USING THE METHOD

摘要

The present invention relates to a method of re-balancing a redox state to maximize production of a fermentation product in an E. coli strain and an E. coli strain for producing a highly productive fermentation product developed using the method. More specifically, the present invention relates to (1) (2) introducing the fdh1 gene of the yeast whose 5'UTR sequence is regulated into the E. coli strain and / or (2) regulating the PDH complex in the E. coli strain to balance the redox state so that the fermentation product, And an E. coli strain for producing butanol produced by using the above method. The method for maximizing fermentation product production in E. coli strains according to the present invention is characterized in that fdh1 It is possible to produce a fermented product with high efficiency without controlling the expression level of the gene and / or by controlling the expression level of the FDH1 complex.