Method of Inducing Mesenchymal Stem Cell to Differentiate into GABAergic Neuronal Cell and Compostion Comprising BDNF for Inducing Differentiation into GABAergic Neuronal Cell

摘要

The present invention relates to a method of differentiating mesenchymal stem cells into GABAergic neurons and a composition for inducing GABAergic neural differentiation of mesenchymal stem cells comprising BDNF. The method of differentiating the mesenchymal stem cells of the present invention into GABA neurons differentiates the mesenchymal stem cells into GABA neurons in a large amount by using BDNF, It can serve as an excellent source of therapy. In addition, the composition for inducing differentiation of GABA neurons in mesenchymal stem cells comprising BDNF of the present invention massively differentiates mesenchymal stem cells into GABA neurons in vitro and in vivo, so that mesenchymal stem cell transplantation It can be expected to be used for treatment.