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EXPRESS METHOD OF OBTAINING RESTORED FORM OF COFERMENT Q ON TO THE BASIS CATALYSTS FOR USE B PHARMACEUTICAL AND FOOD COMPOSITIONS
EXPRESS METHOD OF OBTAINING RESTORED FORM OF COFERMENT Q ON TO THE BASIS CATALYSTS FOR USE B PHARMACEUTICAL AND FOOD COMPOSITIONS
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机译:在B类药品和食品成分的基础催化剂上获取还原形式的交易Q的快速方法。
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摘要
1. A method for producing reduced coenzyme Qvklyuchaet coinciding with the method of US 2011123505 (A1) a step (i) prior dissolution in ethanol, ascorbic acid and oxidized form of coenzyme Q, but combined in a molar ratio of at least 5: 1, characterized in that it includes the further sequential steps of : (ii) the addition of trace catalyst - Cuv ions as copper sulfate pentahydrate solution (CuSO · 5HO); (Iii) catalytic reduction coenzyme Qc form its reduced form (ubiquinol); (Iv) crystallization and isolating the final product - the reduced coenzyme Qc vodoy.2 its subsequent washing. A method according to claim 1, characterized in that in step (i) using 95% solvent etanol.3. A method according to claim 1, characterized in that after evaporating off the ethanol may be recovered for subsequent ispolzovaniya.4. A method according to claim 1, characterized in that in step (iii) catalytic reduction proceeds Coenzyme Q (ubiquinone) quantitatively at 25 ° C.5. A method according to claim 1, characterized in that the amount of the final product is increased 4-5 times when coenzyme Qprovoditsya catalytic reduction at 60 ° C.6. A method according to claim 1, characterized in that in step (iv) in the resulting solution was retreaded coenzyme Qdobavlyayut 10 vol.% Vody.7. A method according to claim 1, characterized in that selected in step (iv) reduced coenzyme Qmozhet be stabilized ascorbic acid (weight ratio KoQ:. AK 1: 1) in an aqueous solution by introducing a solubilizer and then receiving a gel containing 10% the reduced coenzyme KoQ.8. A method according to claim 1, characterized in that selected in step (iv) reduced coenzyme hundred be Qmozhet
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