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A NEW METASTATIC HUMAN TUMOR ASSOCIATED MOLECULE, METHODS TO DETECT BOTH ACTIVATED GENE AND PROTEIN AND TO INTERFERE WITH GENE EXPRESSION
A NEW METASTATIC HUMAN TUMOR ASSOCIATED MOLECULE, METHODS TO DETECT BOTH ACTIVATED GENE AND PROTEIN AND TO INTERFERE WITH GENE EXPRESSION
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机译:一种新型的转移性人类肿瘤相关分子,检测活化的基因和蛋白质并干扰基因表达的方法
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摘要
This disclosure characterizes the function and the expression of the human protein encoded by tm9sf4. The protein is highly expressed in malignant tumor cells and therefore is a novel marker for malignancy. Moreover, the protein is involved in the phagocytotic character of tumor cells. This disclosure provides methods and tools to diagnose and follow up malignancy of tumors. Furthermore, means to inhibit phagocytotic character of tumor cells as well as means to treat cancer are provided.
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