A method of mass analysis comprises: generating ions from the sample; delivering the ions to a quadrupole; applying a radio frequency voltage, V, to rods of the quadrupole such that the instantaneous electrical potential of each rod is out of phase with each adjacent rod and a non-oscillatory voltage, U, across each pair of adjacent rods such that a subset of the ions having a range of mass-to-charge (m/z) ratios are selectively transmitted through the quadrupole; varying at least one of voltage U and voltage V such that the range of selectively transmitted m/z ratios is caused to vary and varying at least one additional operational parameter; acquiring a data set comprising a series of temporally-resolved images of spatial distribution patterns of transmitted ions at each combination of U, V and the at least one additional operating parameter; and mathematically deconvolving the data set to generate mass spectra.
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机译：质量分析的方法包括：从样品产生离子;将离子输送到四极杆;将射频电压 V 施加到四极杆，以使每个杆的瞬时电势与每个相邻杆的异相和非振荡电压， U， 分布在每对相邻的棒上，以使一部分离子具有质荷比（ m / < I> z ）比率通过四极有选择地传输;改变电压 U 和电压 V 中的至少一个，以使选择性传输的m / z比的范围为导致变化并改变至少一个附加的运行参数;获取数据集，该数据集包括一系列在 U，V 和至少一个附加操作参数的每种组合下的透射离子空间分布模式的时间分辨图像;并对数据集进行数学解卷积以生成质谱图。
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