Phospholipid analysis utilising a novel, data independent, mode of acquisition on a QToF instrument in combination with a scanning quadrupole mass filter and an ultra fast data acquisition system

摘要

Here we have shown the benefits of SONAR for the application of lipid analysis including: 1. Cleaner spectra compared to other DIA methods. 2. High spectra/second scan rate compatible with HR MS. 3. Increased confidence in identification through selectivity. 4. Cataloguing of a complex sample within one experiment. 5. Unbiased data acquisition within a targeted mass range.