CELL REPROGRAMMING INCLUDING APPLICATION OF EPIGENETIC AND NON-EPIGENETIC BASE TO ARTIFICIAL PLURIPOTENT STEM CELL INDUCTION

摘要

PROBLEM TO BE SOLVED: To provide a cell reprogramming including an application of an epigenetic and non-epigenetic base to artificial pluripotent stem cell induction.SOLUTION: Mathematical and statistical image analysis method and system are applied to increase and improve a reprogramming process of a cell, and a patient-derived cell is modified into a stem cell that meets an order, for example. In a specific embodiment, the present invention is a method for identifying artificial pluripotent stem cell, in which the method includes: (a) a step of obtaining an image of one or more cells; (b) a step of expressing the image as a large number of pixels; (c) a step of extracting characteristic of one or more images from the large number of pixels by using a processor; and (d) a step of comparing the characteristic of the one or more images with the characteristic of an image obtained from one or more pluripotent stem cells, in which the processor performs one or more statistical comparison methods to compare the characteristic of the image, by which an artificial pluripotent stem cell is identified.SELECTED DRAWING: Figure 2