Oxygen content of the storage solution of organs and tissues, in order to increase the stability, and shelf life, formulations containing poly (0-2- hydroxyethyl) starch

摘要

Save for the solution of the organs and tissues with a improved prescription. Improved solution contains two separate solutions. First solution, one or more salts, water, dissolved oxygen, comprise poly (0-2- hydroxyethyl) starch, lactobionic acid, adenosine, raffinose, and allopurinol, the first solution is at least 7.0 the pH, preferably a pH of about 7.3 about 8.2, second solution, water and reduced glutathione, pH less than 7.0, preferably comprise from about 3 to 6 of pH, where the oxygen is parenchyma It has been removed. The two solutions are mixed in use, with improved stability, comprising oxygen in order to prevent ischemia in organs to be stored, resulting in preservation solution for organs and tissues. The present invention also includes a kit containing the above two formulations.