A highly efficient method for the reprogramming of differentiated cells and the generation of animal and embryonic stem cells from the reprogrammed cells

摘要

The present invention relates generally to the field of somatic cell nuclear transfer (SCNT) and to the creation of cloned animals and cells. The disclosure relates to a method of cloning a mammal, obtaining pluripotent cells such as embryonic stem cells, or for reprogramming a mammalian cell using an oocyte and a fertilized embryo.