Recognition of cellular target binding by bioactive agents using intracellular bioluminescence resonance energy transfer

摘要

The present invention provides compositions and methods for the detection and analysis of intracellular binding of bioactive agents to cellular targets. In particular, detecting and analyzing the interaction between a cell target and a bioactive agent with a phosphor, a cell target fused with a bioluminescent reporter, or a bioactive agent bound to a part, component or subunit of the bioluminescent reporter A method is provided herein. [Selection] Figure 1