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Treatment of MSRA-related diseases by inhibition of natural antisense transcripts against methionine sulfoxide reductase A (MSRA)

机译:通过抑制蛋氨酸亚砜还原酶A(MSRA)的天然反义转录本来治疗MSRA相关疾病

摘要

The present invention relates to antisense oligonucleotides that modulate the expression of and/or function of Methionine Sulfoxide Reductase A (MSRA), in particular, by targeting natural antisense polynucleotides of Methionine Sulfoxide Reductase A (MSRA). The invention also relates to the identification of these antisense oligonucleotides and their use in treating diseases and disorders associated with the expression of MSRA.
机译:本发明涉及调节蛋氨酸亚砜还原酶A(MSRA)的表达和/或功能的反义寡核苷酸,特别是通过靶向蛋氨酸亚砜还原酶A(MSRA)的天然反义多核苷酸。本发明还涉及这些反义寡核苷酸的鉴定及其在治疗与MSRA表达有关的疾病和病症中的用途。

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