首页> 外国专利> Composition for stabilizing a fusion protein in which a protein and an Fc domain are fused

Composition for stabilizing a fusion protein in which a protein and an Fc domain are fused

机译:用于稳定融合了蛋白质和Fc结构域的融合蛋白的组合物

摘要

The present invention relates to a composition for stabilizing a fusion protein of a physiologically active protein and an Fc domain, and uses an ammonium salt or a composition containing an ammonium salt and a succinate to make a protein and Fc domain. The present invention relates to a method for stabilizing a fusion protein. Since the composition containing an ammonium salt or an ammonium salt and succinate according to the present invention effectively inhibits the aggregation of the Fc-fusion protein, the fusion protein can be stored for a long time. It can be widely used in the medical field using fusion proteins.
机译:本发明涉及用于稳定生理活性蛋白和Fc结构域的融合蛋白的组合物,并且使用铵盐或包含铵盐和琥珀酸盐的组合物来制备蛋白和Fc结构域。本发明涉及稳定融合蛋白的方法。由于根据本发明的包含铵盐或铵盐和琥珀酸盐的组合物有效地抑制了Fc融合蛋白的聚集,因此可以长时间保存融合蛋白。使用融合蛋白可广泛用于医学领域。

著录项

相似文献

  • 专利
  • 外文文献
  • 中文文献
获取专利

客服邮箱:kefu@zhangqiaokeyan.com

京公网安备:11010802029741号 ICP备案号:京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有
  • 客服微信

  • 服务号