The method sterilization of separation membrane module, the method of manufacturing chemicals by continuous fermentation, and membrane separation-type continuous fermentation apparatus

摘要

in a short time, steam sterilization method of steam sterilization reliably separation membrane module, continuous chemical method of production by fermentation, and to provide a membrane separation type continuous fermentation apparatus. Steam sterilization method of the separation membrane module of the present invention, the secondary side of the separation membrane module, as the filling rate at surrounded by the portion which is subjected to the filtration of the separation membrane space is less than 70%, the atmospheric pressure and boiling the liquid supply step of supplying 80 more liquids under (step S1), so as to be the filling factor of the liquid supplied to the secondary side of the separation membrane module in the liquid supplying step and 70% Liquid enclosing step of enclosing (step S2), sterilization of the supplies steam to the primary side of the separation membrane module, the temperature raising step of raising the temperature to a sterilization temperature (step S3), the predetermined time sterilization at a predetermined sterilization temperature process (step S4), and is characterized in that it comprises.