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Smallpox DNA vaccines that induce immune responses and antigens therein
Smallpox DNA vaccines that induce immune responses and antigens therein
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机译:天花DNA疫苗,可在其中诱导免疫应答和抗原
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摘要
The present invention relates to DNA vaccines that are capable of generating a protective immune response in mammals against a pox virus, and comprises at least one DNA plasmid capable of expressing a plurality of VACV MV antigens, and at least one DNA plasmid capable of expressing a plurality of VACV EV antigens. Also, the present invention relates to methods of inducing a protective immune response in a mammal to pox virus, including a neutralizing antibody response, comprising: injecting into tissue of said mammal said DNA vaccine.
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