Cell imaging method and imaging agent using fluorescently labeled sugar derivative bound with coumarin derivative

摘要

An object of the present invention is to provide a sugar derivative emitting a blue fluorescent color that can be used for imaging of cells or intracellular molecules, and a cell imaging method using the derivative. Another object of the present invention is to provide a method for accurately detecting cancer cells by imaging, and an imaging agent used in the method. According to the present invention, a fluorescently labeled sugar having 3-carboxy-6,8-difluoro-7-hydroxycoumarin or 3-carboxymethyl-6,8-difluoro-7-hydroxy-4-methylcoumarin as a fluorescent molecular group in the molecule Derivatives, and cell imaging agents and imaging methods using the derivatives are provided. The present invention also provides a cancer cell imaging agent and an imaging method using an L-glucose derivative having the fluorescent molecular group in the molecule.