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METHODS OF TREATING PRURITIC CONDITIONS MEDIATED THROUGH NON-HISTAMINERGIC MECHANISMS IN DIABETIC PATIENTS
METHODS OF TREATING PRURITIC CONDITIONS MEDIATED THROUGH NON-HISTAMINERGIC MECHANISMS IN DIABETIC PATIENTS
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机译:通过非组织学机制治疗糖尿病患者的病情的方法
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摘要
Described herein are methods of treating a mammal in need of treatment for non-histaminic pruritus by administering to the mammal in need thereof a therapeutically effective amount of RS-norketotifen or a pharmaceutically acceptable salt thereof, thereby reducing the desire to scratch in the mammal. Non-histaminergic types of pruritus are resistant to treatment with selective histamine H-1-, H-2- and H-4-receptor inhibitors. In certain aspects, the non-histaminergic pruritus is associated with diabetes.
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