AGARICUS BLAZEI MURILL EXTRACTS, METHODS FOR INHIBITING LEGUMAIN USING THE SAME, AND METHODS FOR TREATING TUMORS USING THE SAME

摘要

Extracts of Agaricus blazei Murill have been found to have anti-tumor activity. In particular, a polar, high molecular weight fraction of an Agaricus blazei Murill extract has been found which has an inhibitory effect on legumain activity. Extracts of Agaricus blazei Murill can be used in a pharmaceutical composition to inhibit cysteine protease legumain in a patient suffering from a tumor thereby treating the tumor and preventing new tumors.