首页>
外国专利>
VACCINATION WITH RECOMBINANT MYCOBACTERIUM TUBERCULOSIS PknD ATTENUATES BACTERIAL DISSEMINATION TO THE BRAIN
VACCINATION WITH RECOMBINANT MYCOBACTERIUM TUBERCULOSIS PknD ATTENUATES BACTERIAL DISSEMINATION TO THE BRAIN
展开▼
机译:重组结核分枝杆菌PknD疫苗接种可减轻细菌对脑的扩散。
展开▼
页面导航
摘要
著录项
相似文献
摘要
Vaccines comprising Mycobacterium tuberculosis (M. tuberculosis) PknD sensor polypeptides, compositions, kits, and methods of use for treating central nervous system tuberculosis are disclosed. More specifically, the disclosure provides a method for treating or preventing central nervous system (CNS) tuberculosis (TB) in a subject, the method comprises administering to the subject a therapeutically effective amount of a vaccine comprising an M tuberculosis PknD sensor polypeptide, or an immunogenic fragment for inhibiting or preventing M tuberculosis bacterial invasion of brain microvascular endothelia.
展开▼