首页> 外国专利> MUTEINS WITH TEAR LIPOCALIN HAVING AFFINITY TO HUMAN C-MET RECEPTOR TYROSINE KINASE AND METHODS FOR OBTAINING THE SAME

MUTEINS WITH TEAR LIPOCALIN HAVING AFFINITY TO HUMAN C-MET RECEPTOR TYROSINE KINASE AND METHODS FOR OBTAINING THE SAME

机译:对人C-MET受体酪氨酸激酶具有亲和力的泪脂蛋白突变蛋白及其获得方法

摘要

The present invention relates to novel muteins derived from human tear lipocalin having affinity to human c-Met receptor tyrosin kinase (c-Met). The invention also refers to a corresponding nucleic acid molecule encoding such a mutein and to a method for its generation. The invention further refers to a method for producing such a mutein. Finally, the invention is directed to a pharmaceutical composition comprising such a lipocalin mutein as well as to various uses of the mutein.
机译:本发明涉及衍生自人眼泪脂蛋白的新型突变蛋白,其对人c-Met受体酪氨酸激酶(c-Met)具有亲和力。本发明还涉及编码这种突变蛋白的相应核酸分子及其产生方法。本发明还涉及生产这种突变蛋白的方法。最后,本发明涉及包含这种脂钙蛋白突变蛋白的药物组合物以及突变蛋白的各种用途。

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