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Method For Highly Sensitive Detection of Biomarkers for Diagnostics
Method For Highly Sensitive Detection of Biomarkers for Diagnostics
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机译:用于诊断的生物标志物的高灵敏度检测方法
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摘要
This disclosure provides, among other things, a nanosensor comprising a substrate and one or a plurality of pillars extending from a surface of the substrate, where the pillars comprise a metallic dot structure, a metal disc, and a metallic back plane. The nanosensor comprises a molecular adhesion layer that covers at least a part of the metallic dot structure, the metal disc, and/or the metallic back plane and a capture agent bound to the molecular adhesion layer. The nanosensor amplifies a light signal from an analyte, when the analyte is specifically bound to the capture agent.
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