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USE OF FUMARIC ACID DERIVATIVES FOR TREATING CARDIAC INSUFFICIENCY, AND ASTHMA

机译:使用富马酸衍生物治疗心脏功能不全和哮喘

摘要

According to a first aspect the invention relates to the use of fumaric acid derivatives selected from the group consisting of dialkyl fumarates, monoalkyl hydrogen fumarates, fumaric acid monoalkyl ester salts, fumaric acid monoamides, monoamido fumaric acid salts, fumaric acid diamides, monoalkyl monoamido fumarates, carbocyclic and oxacarbocyclic oligomers of these compounds and mixtures thereof for preparing a drug for the treatment or prevention of cardiac insufficiency, in particular left ventricular insufficiency, myocardial infarction and angina pectoris.;According to a second aspect the invention relates to the use of fumaric acid derivatives, selected from the group consisting of dialkyl fumarates, monoalkyl hydrogen fumarates, fumaric acid monoalkyl ester salts, fumaric acid monoamides, monoamido fumaric acid salts, fumaric acid diamides, monoalkyl monoamido fumarates, carbocyclic and oxacarbocyclic oligomers of these compounds and mixtures thereof for preparing a drug for the treatment of asthma and chronic obstructive pulmonary diseases, especially asthma caused by allergies, infections, analgesics, job conditions or physical effort, mixed forms of asthma, or asthma cardiale.
机译:根据第一方面,本发明涉及选自富马酸二烷基酯,富马酸单烷基氢盐,富马酸单烷基酯盐,富马酸单酰胺,单酰胺基富马酸盐,富马酸二酰胺,单烷基富酰胺酸富马酸衍生物的用途。 ,这些化合物的碳环,碳环和氧碳环低聚物及其混合物,用于制备用于治疗或预防心脏功能不全,特别是左心室功能不全,心肌梗塞和心绞痛的药物。根据第二方面,本发明涉及富马酸的用途。酸衍生物,选自富马酸二烷基酯,富马酸单烷基氢盐,富马酸单烷基酯盐,富马酸单酰胺,富马酸单酰胺基富马酸盐,富马酸二酰胺,富马酸单烷基单酰胺基富马酸酯,这些化合物的碳环和氧碳环低聚物及其混合物为药物做准备治疗哮喘和慢性阻塞性肺疾病,特别是由过敏,感染,镇痛药,工作条件或体力劳动,混合形式的哮喘或哮喘引起的哮喘引起的哮喘。

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