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METHOD FOR DIAGNOSIS AND PROGNOSIS OF CHRONIC OBSTRUCTIVE PULMONARY DISEASE (COPD)

机译:慢性阻塞性肺疾病(COPD)的诊断和预后方法

摘要

A method for aiding in categorising or determining prognosis in a subject with COPD, or in selecting a therapeutic strategy for a subject with COPD, or in monitoring disease progression or assessing effectiveness of a treatment regime for COPD, the method comprising the step of assessing the antibody response to carbonylated vimentin in a sample obtained from the subject. The method may further comprise the step of selecting a treatment regime making use of the information on the antibody response to carbonylated vimentin in the sample. The step of assessing of the antibody response to carbonylated vimentin may comprise the step of determining the ratio of IgG to IgM in the antibody response to carbonylated vimentin.
机译:一种用于帮助对患有COPD的受试者进行分类或确定其预后,或为患有COPD的受试者选择治疗策略,或监测疾病进展或评估COPD治疗方案的有效性的方法,该方法包括以下步骤:从受试者获得的样品中抗体对羰基化波形蛋白的反应。该方法可以进一步包括利用关于样品中对羰基化波形蛋白的抗体应答的信息来选择治疗方案的步骤。评估抗体对羰基波形蛋白的反应的步骤可以包括确定抗体对羰基波形蛋白的反应中IgG与IgM之比的步骤。

著录项

  • 公开/公告号US2016097778A1

    专利类型

  • 公开/公告日2016-04-07

    原文格式PDF

  • 申请/专利权人 IMPERIAL INNOVATIONS LIMITED;

    申请/专利号US201414890948

  • 发明设计人 PAUL ARCHIBALD KIRKHAM;

    申请日2014-05-12

  • 分类号G01N33/68;C07K16/42;

  • 国家 US

  • 入库时间 2022-08-21 14:32:46

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