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Treatment and prevention of learning and memory disorders

机译:治疗和预防学习记忆障碍

摘要

The present invention generally relates to compositions and methods for transdermal drug delivery, including treatment and prevention of learning and memory disorders, and enhancement of learning or memory. In some cases, the composition may include nitric oxide. The nitric oxide may be present within a first phase comprising a lecithin, such as phosphatidylcholine. In certain embodiments, the lecithin is present in liposomes, micelles, or other vesicles containing nitric oxide. The composition can take the form of a gel, a cream, a lotion, an ointment, a solution, a solid “stick,” etc., that can be rubbed or sprayed onto the skin. Other aspects of the present invention are generally directed to methods of making or using such compositions, methods of promoting such compositions, kits including such compositions, or the like.
机译:本发明总体上涉及用于透皮药物递送的组合物和方法,包括治疗和预防学习和记忆障碍,以及增强学习或记忆。在某些情况下,组合物可以包含一氧化氮。一氧化氮可以存在于包含卵磷脂的第一相中,例如磷脂酰胆碱。在某些实施方案中,卵磷脂存在于脂质体,胶束或其他含有一氧化氮的囊泡中。所述组合物可以采取凝胶,乳膏,洗剂,软膏,溶液,固体“棒”等的形式,其可以被摩擦或喷雾到皮肤上。本发明的其他方面通常涉及制备或使用此类组合物的方法,促进此类组合物的方法,包括此类组合物的试剂盒等。

著录项

  • 公开/公告号US9480708B2

    专利类型

  • 公开/公告日2016-11-01

    原文格式PDF

  • 申请/专利权人 TRANSDERMAL BIOTECHNOLOGY INC.;

    申请/专利号US201514924613

  • 发明设计人 NICHOLAS V. PERRICONE;

    申请日2015-10-27

  • 分类号A61K9/127;A61K33;A61K9/50;A61K9;A61K9/10;A61K47/24;A61K31/685;A61K9/48;

  • 国家 US

  • 入库时间 2022-08-21 14:32:32

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