An Analogue of Epothilone, their use for the preparation of a Drug and a Pharmaceutical composition suitable for parenteral Administration.

摘要

It is similar to cycloacetone represented by formula (1),And any solution or hydrate thereof for the treatment of patients requiring intravenous treatment and an effective amount of pharmaceutical ingredients, in which the ingredients in the drug preparation bottle are mixed, including The number of separate containers, similar degreased cyclophosphamide and solvents, therefore, when the components of these containers are mixed, the resulting solution ranges from 2 mg / ml to 4 mg / ml.The solvent consists of a mixture of equal volume of dehydrated ethanol and a suitable non ionized surface substance, expressed by formula (1).Dilute the resulting solution with an appropriate amount of diluent diluent such that the concentration of a similar diluent in the solution ranges from 0.1 mg / ml to 0.9 mg / ml.In the similar formula (1), the cycloacetone used to prepare the medicine and the medicine composition suitable for the parents' use. 3. Claim 3: cyclohexanone similar to that used in claim 1 or claim 2What's called "thinner" is whey ring spray Requirement 4: pharmaceutical ingredients suitable for parental management, characterized by a compound represented by formula (1) and its solution or hydrate; dehydrated alcohol; and an unborn surface. Claim 5: it is in conformity with the composition of claim 4, which is characterized in that the surface is risino oil of poly (Tetraene).