Compound Formulation for oral administration comprising via rosuvastatin and ezetimibe

摘要

A method of preparing the compound formulation. Claim 1: A solid compound formulation for oral administration, the solid compound formulation comprising a part of ezetimibe granules including ezetimibe, wherein said ezetimibe has a particle size distribution where the mean particle size d₍₀ , ₉₎ for the lower margin of 90% is approximately 10 mm or less; and a rosuvastatin blend portion including rosuvastatin or a pharmaceutically acceptable salt thereof. Claim 6: The solid composite formulation of any one of claims 1 to 3,There, the mixture part of rosuvastatina also includes a less basic stabilizer.