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phenylaminopyrimidine-derived compounds, process for obtaining, use of said compounds in cancer treatment and treatment methods

机译:苯氨基嘧啶衍生的化合物,获得方法,所述化合物在癌症治疗中的用途和治疗方法

摘要

phenylaminopyrimidine-derived compounds, process for obtaining, use of said compounds in cancer treatment and treatment methods. The present invention relates to novel phenylaminopyrimidine (fap) derivatives of general formula ie ii: where in formula 1, r1 is: where in formula ii, x + is selected from one of the following compounds: where in formula ii, The compounds of the present invention are potent and non-specific tyrosine kinase inhibitors, and the use of such compounds in the treatment of cancer patients, which involves inhibition of the enzyme tyrosine kinase, is also an object of the present invention.
机译:苯基氨基嘧啶衍生的化合物,获得方法,所述化合物在癌症治疗中的用途和治疗方法。本发明涉及通式即ii的新型苯基氨基嘧啶(fap)衍生物:其中在式1中,r1是:其中在式ii中,x +选自下列化合物之一:其中在式ii中,本发明是有效的和非特异性的酪氨酸激酶抑制剂,这些化合物在治疗癌症患者中的用途,包括抑制酪氨酸激酶的酶,也是本发明的目的。

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