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phenylaminopyrimidine-derived compounds, process for obtaining, use of said compounds in cancer treatment and treatment methods
phenylaminopyrimidine-derived compounds, process for obtaining, use of said compounds in cancer treatment and treatment methods
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机译:苯氨基嘧啶衍生的化合物,获得方法,所述化合物在癌症治疗中的用途和治疗方法
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摘要
phenylaminopyrimidine-derived compounds, process for obtaining, use of said compounds in cancer treatment and treatment methods. The present invention relates to novel phenylaminopyrimidine (fap) derivatives of general formula ie ii: where in formula 1, r1 is: where in formula ii, x + is selected from one of the following compounds: where in formula ii, The compounds of the present invention are potent and non-specific tyrosine kinase inhibitors, and the use of such compounds in the treatment of cancer patients, which involves inhibition of the enzyme tyrosine kinase, is also an object of the present invention.
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