The cell of Candida, and methods to produce one or more of isocitrato, alpha a-ketoglutarate, lactate, succinate, malate, fumarate, citrate and oxaloacetate, acrylate, and to produce a cell.

摘要

Construction of recombinant nucleic acid, cell, and methods for producing lactic acid, and to reduce the activity of pyruvate decarboxylase in a cell. The present invention relates to biocatalysts that are cells, optimally of phenotype negative for wild apple tree, comprising vectors of speech coding genes heteru00f3logos cell that allow increased production of organic products.More specifically, the invention relates to a cell of Candida genetically modified, methods to make the cells of Candida, and its use in the production of organic products, especially lactic acid.