METHOD OF OBTAINING 19-NORPREGN-4-EN-3,20-DION-17 (Α) -OLA (GESTONORONA) AND INTERMEDIATE PRODUCTS FOR IT

摘要

The present invention relates to a new stereoselective method for the synthesis of 17 (α) -17-acetyl-17-hydroxy-estr-4-en-3-one having the formula (I), as well as to new intermediates for this method. 17 (α) -17-acetyl-17-hydroxy-estr-4-en-3-one (gestonoron) is an important intermediate for the synthesis of active ingredients with progestogenic activity, such as gestonoron capronate and nomegestrol acetate.