Method for the manufcture of a preparation comprising virus or viral antigens and various aspects related thereto, uses thereof and a split virus vaccine preparation obtained by the method

摘要

The present invention provides a method for the manufacture of a preparation comprising virus antigens comprising a) inoculation of cells with infectious virus in a fluid, b) propagation of said virus in said cells, c) collecting said propagated virus, d) inactivating said collected virus, and e) treating said inactivated virus with a detergent, resulting in a preparation comprising viral antigens.