Pharmaceutical composition comprising as an active ingredient a highly pure 7-chloro-5-hydroxy-1-2-methyl-4-(2-methyl¬benzoyl¬amino)benzoyl-2,3,4,5-tetrahydro-1h-1-benzazepine having a purity of more than 99.5 , or a salt thereof, or a pharmaceutically acceptable salt thereof

摘要

This invention provides a process for preparing benzazepine compounds of the formula (1): wherein X 1 is a halogen atom, R 1 and R 2 are a lower alkyl group, or salts thereof as well as intermediate benzoic acid compounds in high yield and high purity on industrial scale, which are useful as an intermediate for preparing a pharmaceutically active 2,3,4,5-tetrahydro-1H-1-benzazepine compound having vasopressin antagonistic activity.