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12443-a BET Novel 124triazolo43-aquinoxaline amino phenyl derivatives or pharmaceutically acceptable salts thereof preparation method therof and pharmaceutical composition for use in preventing or treating bromodomain extra-terminalBET protein activity related diseases containing the same as an active ingredient
12443-a BET Novel 124triazolo43-aquinoxaline amino phenyl derivatives or pharmaceutically acceptable salts thereof preparation method therof and pharmaceutical composition for use in preventing or treating bromodomain extra-terminalBET protein activity related diseases containing the same as an active ingredient
The present invention relates to a [1,2,4] triazolo [4,3-a] quinolizinaminophenyl derivative or a pharmaceutically acceptable salt thereof, a process for preparing the same, and a bromodomain extra- And a pharmaceutical composition for preventing or treating a protein-related disease. The [1,2,4] triazolo [4,3-a] quinolizine aminophenyl derivative according to the present invention excellently inhibits the binding of BRD4 protein, one of the BET protein family, at low concentration, Therefore, it can be useful for preventing or treating diseases related to BET protein, particularly cancer or autoimmune diseases.
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