ORAL SOLID DOSAGE FORMULATION OF 1,1-DIMETHYLETHYL (1S)-1-{(2S,4R)-4-(7CHLORO-4METHOXYISOQUINOLIN-1-YLOXY)-2-({(1R,2S)-1-(CYCLOPROPYLSULFONYL)CARBAMOYL-2ETHENYLCYCLOPROPYL}CARBAMOYL)PYRROLIDIN-1-YLCARBONYL}-2,2-DIMETHYLPROPYLCARBAMATE

摘要

The present invention is directed to an oral solid dosage formulation of Asunaprevir 1 1 dimethylethyl [(1S) 1 {[(2S 4R) 4 (7 chloro 4methoxyisoquinolin 1 yloxy) 2 ({(1R 2S) 1 [(cyclopropylsulfonyl)carbamoyl] 2 ethenylcyclopropyl}carbamoyl)pyrrolidin 1 yl]carbonyl} 2 2 dimethylpropyl]carbamate and to methods of using the formulation in the treatment and/or inhibition of the hepatitis C virus and infections caused thereby.