A NOVEL ORAL FORMULATION FOR CANCER THERAPY, LOADED IN A SLOW RELASE MATRIX FOR TARGETED DELIVERY

摘要

The present invention, provide an anti-cancer formulation, incorporated in the hydrogel.. It . selectively cause apoptosis of cancer cells, leaving the healthy cells unaffected. The anti-cancer formulation comprises of all aqueous leaf extracts of Belada mara (Aegle marmelos), Oxalis corniculaia; cotyledons of the seed of custard apple {Annona reticulate), seeds of Fenugreek {Trigonella foenum- graecum). Ginseng from the plant Panax ginseng and Newcastle disease virus suspended in IX Phosphate buffer saline, all at declared proportions. Its hydrogel based targeted oral delivery for slow release in the intestine has been developed. The hydrogel comprises agarose and protein in phosphate buffer saline, polyethelene glycol and glycerol. The contents of the hydrogel are non-toxic and are consumed as food or for therapy. The hydrogel can be made for target specific (pH specific) release in intestine or in stomach by altering the buffer pH during the production.