ONE POT SYNTHESIS OF 2-AMINO-4, 6-DIARYL PYRIMIDINES USING CESIUM HYDROXIDE- ALUMINA AS A HETEROGENEOUS BASIC CATALYST

摘要

The present invention relates to the one pot synthesis of 2-amino-4, 6-diaryl pyrimidines from acetophenones, aromatic aldehydes and guanidine hydrochloride using heterogeneous basic catalyst CsOH-A12O3. Along with the good yield, significance of the heterogeneous catalyst over the homogeneous counterpart is its ease of separation and reusability without loss of activity.