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agonistic anti-Notch3 and use in treating diseases related to Notch3
agonistic anti-Notch3 and use in treating diseases related to Notch3
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机译:激动性抗Notch3及其在治疗与Notch3相关的疾病中的用途
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摘要
An antibody that binds specifically to Notch 3 receptor, wherein the antibody specifically binds to an epitope in SEQ ID NO: 10, and wherein the antibody is an agonist of Notch 3 activates signaling mediated Notch 3 receptor through the Notch 3 receptor independent of ligand binding to Notch 3 receptor.
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机译:特异性结合Notch 3受体的抗体,其中该抗体特异性结合SEQ ID NO:10中的表位,并且其中该抗体是Notch 3的激动剂,通过与配体结合无关的Notch 3受体激活信号传导介导的Notch 3受体。 Notch 3受体。
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