AIRWAY ADMINISTRATION OF TISSUE FACTOR PATHWAY INHIBITOR IN INFLAMMATORY CONDITIONS AFFECTING THE RESPIRATORY TRACT

摘要

The present invention provides methods for the local treatment of acute andchronic extravascular pulmonary fibrin deposition and/or reducing unwantedeffects associated with systemic administration of natural anticoagulants to asubject via airway administration to the subject by intratracheal,intrabronchial or intraalveolar routes of natural anticoagulants orbiologically active derivatives thereof.