SULFONE SUBSTITUTED 2,3-DIHYDROIMIDAZO 1,2-C QUINAZOLINE DERIVATIVES USEFUL FOR TREATING HYPER-PROLIFERATIVE DISORDERS AND DISEASES ASSOCIATED WITH ANGIOGENESIS

摘要

This invention relates to novel sulfone 2I3-dihydroimidazo[1 12-c]quinazolinecompounds, pharmaceuticalcompositions containing such compounds and the use of those compounds orcompositions for phosphotidylinositol-3-kinase (P13K)in-hibition and treating diseases associated with phosphotidylinositol-3-kinase (P13K) activity, in particular treatinghyper-proliferative and/or angiogenesis mediated disorders, as a sole agent orin combination with other active ingredients.