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Design, synthesis and evaluation of procaspase activating compounds as personalized anti-cancer drugs

机译:procaspase激活化合物作为个性化抗癌药物的设计,合成和评估

摘要

Compositions and methods are disclosed in embodiments relating to induction of cell death such as in cancer cells. Compounds and related methods for synthesis and use thereof, including the use of compounds in therapy for the treatment of cancer and selective induction of apoptosis in cells are disclosed. Compounds are disclosed that have lower neurotoxicity effects than other compounds.
机译:在涉及诱导细胞死亡(例如在癌细胞中)的实施方案中公开了组合物和方法。公开了化合物及其合成和使用的相关方法,包括化合物在治疗癌症中的治疗中的用途以及细胞中细胞凋亡的选择性诱导。公开了比其他化合物具有更低的神经毒性作用的化合物。

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