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DESIGN, SYNTHESIS AND EVALUATION OF PROCASPASE ACTIVATING COMPOUNDS AS PERSONALIZED ANTI-CANCER DRUGS

机译:个性化抗癌药中促蛋白酶活性化合物的设计,合成和评价

摘要

Compositions and methods aredisclosed in embodiments relating to induction ofcell death such as in cancer cells. Compoundsand related methods for synthesis and usethere-of, including the use of compounds in therapy forthe treatment of cancer and selective induction ofapoptosis in cells are disclosed. Compounds aredisclosed that have lower neurotoxicity effectsthan other compounds.
机译:组成和方法是在涉及诱导的实施方案中公开细胞死亡,例如癌细胞死亡。化合物以及相关的合成和使用方法包括使用化合物治疗癌症的治疗和选择性诱导公开了细胞凋亡。化合物是披露具有较低的神经毒性作用比其他化合物。

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