Lentiviral vectors containing an MHC class I, MHC class II, or beta-2 microglobulin upstream promoter sequence

摘要

The present invention relates to the insertion of an MHC class I, MHC Class II, or β2 microglobulin upstream promoter sequence into a lentiviral vector to increase viral titers. The invention encompasses these vectors, methods of making the vectors, and methods of using them, including medicinal uses.